Our research

 

Our research focuses on understanding how cancer evolves, progresses, and becomes resistant to treatment. We study the genetic and non-genetic changes that drive this process, using advanced computational and experimental tools in genomics and epigenomics.

By uncovering the mechanisms behind tumor diversity and evolution, our work aims to reveal fundamental principles of cancer biology and guide the development of more effective treatments.

Our laboratory's current projects include:

  1. Investigating the influence of non-genetic/epigenetic alterations, such as DNA methylation or chromatin factors, on pre-malignant and malignant cell states.

  2. Examining the phenotypic plasticity of these pre-malignant and malignant cell states.

  3. Assessing the impact of extrinsic factors, like the tumor microenvironment, on pre-malignant and malignant cell states.

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Join our team.

Our goal is to build a diverse, collaborative community of scientists of all levels.